The truth about trintellix

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    Trintellix (vortioxetine)

    Trintellix vs. other drugs

    You may wonder how certain drugs compare to Trintellix. Below are comparisons between Trintellix and several other medications.

    Trintellix vs.

    Zoloft

    Trintellix and Zoloft (sertraline) are both prescription antidepressant medications. They both affect serotonin, a chemical messenger in the brain, but they work slightly differently.

    Uses

    Trintellix and Zoloft are both FDA-approved for treating major depressive disorder (MDD) in adults.

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    • Zoloft is also approved for treating other conditions, including:

    Dosage and forms

    Trintellix comes as an oral tablet that’s taken once daily. Zoloft comes as an oral tablet and an oral solution. Each form of Zoloft is usually taken once daily.

    Side effects and risks

    Trintellix and Zoloft have some similar side effects, and some that differ.

    Below are examples of these side effects.

    * Trintellix and Zoloft both have a regarding the risk of suicidal thoughts and behaviors in certain people. This is the most serious warning from the Food and Drug Administration (FDA).

    Boxed warnings

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